Edward E Tredget Selected Research

Decorin

1/2021	Stimulation of toll-like receptor pathways by burn eschar tissue as a possible mechanism for hypertrophic scarring.
11/2016	Serum Decorin, Interleukin-1β, and Transforming Growth Factor-β Predict Hypertrophic Scarring Postburn.
8/2015	A novel subpopulation of peripheral blood mononuclear cells presents in major burn patients.
1/2015	MicroRNA 181b regulates decorin production by dermal fibroblasts and may be a potential therapy for hypertrophic scar.
10/2012	Differential expression of class I small leucine-rich proteoglycans in an animal model of partial bladder outlet obstruction.
9/2012	Deep dermal fibroblasts refractory to migration and decorin-induced apoptosis contribute to hypertrophic scarring.
3/2012	Reduced decorin, fibromodulin, and transforming growth factor-β3 in deep dermis leads to hypertrophic scarring.
5/2011	Small leucine-rich proteoglycans, decorin and fibromodulin, are reduced in postburn hypertrophic scar.

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Edward E Tredget Research Topics

Disease

36	Wounds and Injuries (Trauma) 01/2021 - 05/2002
34	Cicatrix (Scar) 01/2022 - 09/2002
29	Burns 01/2022 - 08/2002
17	Hypertrophic Cicatrix (Hypertrophic Scar) 01/2022 - 03/2004
10	Fibrosis (Cirrhosis) 01/2022 - 05/2002
5	Inflammation (Inflammations) 12/2017 - 09/2008
4	Infections 01/2021 - 08/2002
3	Contact Dermatitis (Eczema, Contact) 03/2010 - 09/2008
2	Contracture 01/2017 - 11/2009
2	Urinary Bladder Neck Obstruction (Bladder Neck Obstruction) 03/2015 - 10/2012
1	Reinjuries 01/2022
1	Compartment Syndromes 01/2021
1	Critical Illness (Critically Ill) 12/2018
1	Sepsis (Septicemia) 01/2017
1	Vitamin D Deficiency 09/2016
1	Hypertrophy 03/2015
1	Carcinogenesis 06/2014
1	Ulcer 06/2014
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 07/2012
1	Chemical Burns (Chemical Burn) 07/2012
1	Lung Diseases (Lung Disease) 03/2012

Drug/Important Bio-Agent (IBA)

26	CollagenIBA 01/2022 - 05/2002
8	DecorinIBA 01/2021 - 05/2011
7	CytokinesIBA 12/2017 - 07/2005
6	Biological ProductsIBA 01/2022 - 09/2007
6	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2007
5	Transforming Growth Factor beta (TGF-beta)IBA 07/2007 - 09/2002
4	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2022 - 07/2008
4	Conditioned Culture MediaIBA 08/2015 - 01/2007
4	Transforming Growth Factor beta1 (TGF beta 1)IBA 01/2007 - 05/2002
3	Small Leucine-Rich ProteoglycansIBA 01/2021 - 05/2011
3	Transforming Growth Factors (Transforming Growth Factor)IBA 11/2016 - 12/2010
3	Chemokine CXCL12IBA 08/2015 - 09/2011
3	CXCR4 Receptors (CXCR4 Receptor)IBA 08/2015 - 09/2011
3	Collagen Type I (Type I Collagen)IBA 11/2012 - 09/2002
3	Procollagen Type IIBA 11/2012 - 05/2002
3	SilverIBA 03/2010 - 09/2008
3	Interferon-alpha2bIBA 07/2008 - 10/2005
3	Messenger RNA (mRNA)IBA 03/2006 - 05/2002
2	Proteoglycans (Proteoglycan)IBA 01/2022 - 01/2022
2	Extracellular Matrix ProteinsIBA 01/2022 - 03/2004
2	BiglycanIBA 01/2021 - 10/2012
2	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2021 - 05/2011
2	salicylhydroxamic acid (SHAM)IBA 01/2020 - 10/2012
2	Collagen Type III (Type III Collagen)IBA 01/2020 - 03/2004
2	ChemokinesIBA 11/2015 - 09/2014
2	Toll-Like Receptor 4IBA 08/2015 - 05/2011
2	ProcollagenIBA 08/2015 - 03/2004
2	Connective Tissue Growth FactorIBA 11/2012 - 12/2010
2	FibromodulinIBA 03/2012 - 05/2011
2	InterferonsIBA 09/2011 - 10/2005
2	Dinitrochlorobenzene (DNCB)IBA 02/2010 - 09/2008
2	AminoglycosidesIBA 07/2007 - 02/2004
2	Neutralizing AntibodiesIBA 07/2007 - 01/2007
2	Hydroxyproline (4 Hydroxyproline)IBA 01/2007 - 01/2004
1	Protein Isoforms (Isoforms)IBA 01/2022
1	Colloids (Colloid)IBA 08/2021
1	AlbuminsIBA 08/2021
1	Crystalloid SolutionsIBA 08/2021
1	PutrescineIBA 01/2020
1	Therapeutic UsesIBA 01/2020
1	Amino Acids FDA Link 01/2020
1	Protein Glutamine gamma Glutamyltransferase 2IBA 01/2020
1	Lysine (L-Lysine)FDA Link 01/2020
1	SiliconesIBA 05/2017
1	Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA 01/2017
1	PlasticsIBA 01/2017
1	Alkaline PhosphataseIBA 12/2016
1	Bone Morphogenetic Protein 4IBA 12/2016
1	HydrogelsIBA 12/2016
1	EnzymesIBA 11/2016
1	ImmunosorbentsIBA 11/2016
1	Vitamin D FDA LinkGeneric 09/2016
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 12/2015
1	Tadalafil (Cialis)FDA Link 03/2015
1	Prednisone (Sone)FDA LinkGeneric 03/2015
1	MicroRNAs (MicroRNA)IBA 01/2015
1	CXC ChemokinesIBA 09/2014
1	CTCE-9908IBA 09/2014
1	SolutionsIBA 08/2014
1	matrigelIBA 02/2013
1	HSP47 Heat-Shock Proteins (Heat Shock Protein 47)IBA 11/2012
1	ChlorineIBA 07/2012
1	Oxygen (Dioxygen)IBA 03/2012

Therapy/Procedure

10	Therapeutics 01/2021 - 03/2006
4	Lasers (Laser) 01/2022 - 11/2012
4	Resuscitation 08/2021 - 09/2005
3	Aftercare (After-Treatment) 09/2011 - 11/2002
2	Skin Transplantation (Skin Grafting) 01/2021 - 03/2012
2	Blood Transfusion (Blood Transfusions) 10/2019 - 12/2018
2	Artificial Skin 07/2015 - 10/2011
2	Transplantation 03/2011 - 01/2006
1	Laser Therapy (Surgery, Laser) 01/2022
1	Abdominoplasty 01/2021
1	Artificial Respiration (Mechanical Ventilation) 10/2019
1	Radiotherapy 06/2014
1	Stem Cell Transplantation 02/2013
1	Extracorporeal Membrane Oxygenation 07/2012
1	Length of Stay 03/2012
1	Long-Term Care 03/2012